Document Type : Review
Department of Medical Services and Techniques, Vocational School of Health Services, Firat University, Elazig, Turkey
Department of Medical Microbiology and Immunology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur, Malaysia
The Center for Immunology and Infectious Diseases, UC Davis, Davis, California, USA
Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, USA
Department of Animal Sciences, Center for Food Animal Health, Ohio Agricultural Research and Development Center, 1680 Madison Avenue, Wooster, OH 44691, USA
The novel coronavirus disease 2019 (COVID-19) is a huge global public health threat which affected millions of people and have been causing high mortalities. Coronaviruses have the largest genomes for RNA viruses, enveloped and single-stranded. They mainly cause respiratory disease with incidences of enteric problems and affecting the liver and neurological system in animals and humans. The rapid diagnosis of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection is required for better control of spread of evolving mutant viruses. This review article aims to gather insights on the epidemiology, diagnosis and treatment of SARS-CoV-2 infection. In conclusion, apart from the COVID-19 disease epidemiology, a better understanding of the available effective, rapid and sensitive tests for SARS-CoV-2 diagnosis and the novel drugs for treatment both prophylactically and therapeutically are necessary to mitigate any future risks of infection.