Insights to the epidemiology, diagnosis and treatments of SARS-CoV-2

Document Type : Review


1 Department of Medical Services and Techniques, Vocational School of Health Services, Firat University, Elazig, Turkey

2 Department of Medical Microbiology and Immunology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur, Malaysia

3 The Center for Immunology and Infectious Diseases, UC Davis, Davis, California, USA

4 Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, USA

5 Department of Animal Sciences, Center for Food Animal Health, Ohio Agricultural Research and Development Center, 1680 Madison Avenue, Wooster, OH 44691, USA



The novel coronavirus disease 2019 (COVID-19) is a huge global public health threat which affected millions of people and have been causing high mortalities. Coronaviruses have the largest genomes for RNA viruses, enveloped and single-stranded. They mainly cause respiratory disease with incidences of enteric problems and affecting the liver and neurological system in animals and humans. The rapid diagnosis of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection is required for better control of spread of evolving mutant viruses. This review article aims to gather insights on the epidemiology, diagnosis and treatment of SARS-CoV-2 infection. In conclusion, apart from the COVID-19 disease epidemiology, a better understanding of the available effective, rapid and sensitive tests for SARS-CoV-2 diagnosis and the novel drugs for treatment both prophylactically and therapeutically are necessary to mitigate any future risks of infection.


Main Subjects