Evaluation of Antibiotic Resistance to Fluoroquinolones and Third Generation Cephalosporines in Iranian Clinical Isolates of Salmonella spp.

Document Type: Research Article

Authors

1 Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran

2 Department of Parasit ology, Pasteur Institute of Iran, Tehran, Iran

3 Department of Hepatitis and AIDS, Pasteur Institute of Iran, Tehran, Iran.

4 Department of Hepatitis and AIDS, Pasteur Institute of Iran, Tehran, Iran

5 Young Researchers and Elite club, Central Tehran Branch, Islamic Azad University, Tehran, Iran

6 Department of Medical Sciences, Isl amic Azad University, Zahedan, Iran

7 Young Researchers Club, Shahrekord Branch, Islamic Azad University, PO BOX 166

Abstract

Salmonella enterica serotypes are one of the most important food borne pathogens and significant public health concerns around the world in humans and other animal species. A total of eighty three epidemiologically unrelated clinical isolates of Salmonella enterica serovars were subjected to antimicrobial susceptibility testing. Eleven isolates (13.1%) which were resistant to at least 4 groups of antimicrobial agents considered as multidrug resistant (MDR) Salmonella serovars. Emergence of MDR Salmonella serovars demonstrates that antimicrobial selection pressure is widespread in our clinical settings. According to the results of antimicrobial susceptibility testing, Salmonella clinical isolates are more susceptible to fluoroquinolones and third generation cephalosporins and these drugs may be used as drugs of choice to treat Salmonella infections.

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