Survey on the prevalence of active infection caused by Helicobacter pylori in the patients carried out endoscopy in Tonekabon

Document Type : Research Article


1 Department of Microbiology, Faculty of Basic Sciences, Islamic Azad University, Tonekabon, Iran

2 Department of Microbiology, Faculty of Basic Sciences, Islamic Azad University, Lahijan, Iran

3 Department of Microbiology, Islamic Azad University, Tonekabon branch, Iran


H.pylori is one of the common infectious agent that involves in acute and chronic gastritis, peptic scar and gastric cancer. The infection episode in children ranges between 10 to 80 percent and the high frequency in developing countries. The goal of this study was to determine the incident of H.pylori in the patients carried out to endoscopy and the effective factors. In this study, 50 patients of 3 to 15 years old range that were admitted in endoscopy ward were studied. After endoscopy, the specimen of gastric mucus was studied using rapid urease Test (RUT). The specimen with urease positive test were taken as the case and specimen with negative urease test were taken as control group and the factors involves in H.pylori were studied. The Odds ratio was calculated in the specimen and confidence interval was performed in 95% probability and the data was analyzed by using common statistical tests. The results showed that of 50 children, 9 patients (18%) were diagnosed with Pelvic ulcer disease (PUD) and positive H.pylori, 5 patients (10%) had gastritis and free from contamination to concerned organism. The 6-15 years old age group showed the highest number of bacteria (30%). Of all the patients subject of study, 7 cases were male (14%) and 8 (16%) were females. 25 patients (54%) had less than high school diploma education and 23 cases (46%) had university education. In this study, age, sex, water consumption, number of family members and the economic-social status were the criteria of study and it was shown that the infection essentially happens in young ages and the chance of infection through contaminated water is high. It is concluded that H.pylori infection is an important factor involving the gastritis and duodenum inflammation.


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