Anti-fungal activity analysis of natural honey samples in Golestan Province against some common dermatophyte strains In-vitro

Document Type : Research Article


1 Young Researchers and Elite Club, Gorgan Branch, Islamic Azad University, Gorgan, Iran

2 Department of Mycology, Gorgan Branch, Islamic Azad University, Gorgan, Iran

3 Department of Microbiology, Gorgan Branch, Islamic Azad University, Gorgan, Iran

4 Department of Microbiology, Damghan Branch, Islamic Azad University, Damghan, Iran

5 Department of Microbiology, Ayatollah Amoli Science and Research Branch, Islamic Azad University, Amol, Iran

6 Yakhteh Golestan Scientific and Industrial Research Co., Gorgan, Iran


One of the superficial problems of public health is mycotic inflection that its incidence is not correctly known. The most important disease of them is dermatophytosis that comes through by dermatophytes as the major group of keratinophilic fungi. Honey is bee product that has been used as a medicine since ancient times in many cultures, and is still used in folk medicine. This study was designed for the purpose of investigation the antifungal potential of 5 honey samples against various dermatophyte strains from 3 genuses, Trichophyton, Microsporum and Epidemophyton by agar dilution technique and determination of the minimum inhibitory concentrations (MIC). The results showed that honey sample JahanNama had the best antidermatophyte effect and Bandargaz had less effect among all 5 honey samples. Also Trichophyton strains had shown the most sensitivity in tests with honey. This study shows that honey samples in Golestan province have an antifungal activity against dermatophytes as superficial infective microorganisms, and their static actions are very logical. So that might confirm the medicinal uses of the studied honey samples for the treatment of coutaneus or other various diseases.


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